A clear, jargon-free guide to what GLP-1 (and GIP) medicines do in the body, why they help with appetite, and what to expect when you start.
GLP-1 medications get talked about a lot, but rarely explained simply. Here's what's actually happening in the body.
GLP-1 (glucagon-like peptide-1) is a hormone your gut naturally releases after you eat. It tells your brain you're full, slows how quickly your stomach empties, and helps your body manage blood sugar. Medicines like Wegovy (semaglutide) mimic this hormone, so those “I've had enough” signals last longer.
Mounjaro (tirzepatide) acts on two hormone pathways — GLP-1 and GIP — which is why many people find its appetite effect especially strong. Your prescriber will help decide which option suits your health profile and goals.
None of this replaces medical advice. A consultation lets a clinician check the treatment is safe and appropriate for you before you begin.
